Table 3:

Associations between mental disorders and psychiatric medication use with long-term weight change following Roux-en-Y gastric bypass.

	Long-term pre-to post-surgery weight change
	B (95% CI)a	DF	P
Any mood disorder (Ref=no history)			0.61
Pre-surgery history only	0.11 (−4.67,4.89)	115
Post-surgery	1.87 (−2.46,6.20)	109
Any eating disorder (Ref=no history)			0.97
Pre-surgery history or post-surgery	0.12 (−6.46,6.69)	61.5
Any psychiatric medication (Ref=no useb)			0.22
Pre-surgery only	−1.22 (−9.78,7.33)	127
Post-surgery	−4.13 (−9.00,0.73)	104

^aEstimated percentage of pre-surgery weight, in years 4–7 associated with the indicated psychiatric variables, after adjustment for the other psychiatric variables, pre-surgery factors related to missing follow-up data (i.e. site and age), and sex, race, and body mass index at pre-surgery, with time entered as a fixed effect. A negative value indicates weight loss. When mood disorder was replaced by anxiety disorder, the estimates (95% CI) were 0.64 (−4.17–5.44) for pre-surgery history only and 2.17 (−2.05–6.40) for post-surgery (p= 0.56). N=72 of 104 RYGB participants.

^bBased on current medication use at pre- and post-surgery assessments. Pre-surgery history of medication use not measured.