Table 3.
Restrictive spirometric pattern (RSP) | True pulmonary restriction | |||
---|---|---|---|---|
TLC < LLN5 (Quanjer) (n = 46) |
TLC < LLN5 (Gothenburg) (n = 53) |
|||
Value | 95% CI | Value | 95% CI | |
RSPLLNSVC (n = 33) | ||||
Sensitivity | 0.24 | 0.13–0.39 | 0.26 | 0.15–0.40 |
Specificity | 0.99 | 0.98–0.99 | 0.99 | 0.98–1.00 |
PPV | 0.52 | 0.30–0.74 | 0.67 | 0.43–0.85 |
NPV | 0.96 | 0.95–0.97 | 0.96 | 0.94–0.97 |
LR+ | 22.4 | 9.2–31.5 | 35.1 | 14.8–83.3 |
LR- | 0.77 | 0.56–0.84 | 0.74 | 0.63–0.87 |
RSP0.7DSVC (n = 31) | ||||
Sensitivity | 0.22 | 0.11–0.36 | 0.21 | 0.11–0.34 |
Specificity | 0.99 | 0.98–1.00 | 0.99 | 0.98–1.00 |
PPV | 0.56 | 0.31–0.78 | 0.61 | 0.36–0.83 |
NPV | 0.96 | 0.95–0.97 | 0.96 | 0.94–0.97 |
LR+ | 25.4 | 10.6–61.5 | 27.6 | 11.1–68.3 |
LR- | 0.79 | 0.68–0.92 | 0.80 | 0.70–0.92 |
Definition of abbreviations: LLN Lower limit of normal; total lung capacity; PPV Positive predictive value, NPV Negative predictive value, LR+ Positive likelihood ratio, LR- Negative likelihood ratio, SVC Slow vital capacity