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. 2020 Feb 27;20:55. doi: 10.1186/s12890-020-1096-z

Table 3.

Validity of restrictive spirometric pattern using slow vital capacity (RSPLLNSVC and RSP0.7SVC) in relation to true pulmonary restriction

Restrictive spirometric pattern (RSP) True pulmonary restriction
TLC < LLN5
(Quanjer)
(n = 46)
TLC < LLN5
(Gothenburg)
(n = 53)
Value 95% CI Value 95% CI
RSPLLNSVC (n = 33)
 Sensitivity 0.24 0.13–0.39 0.26 0.15–0.40
 Specificity 0.99 0.98–0.99 0.99 0.98–1.00
 PPV 0.52 0.30–0.74 0.67 0.43–0.85
 NPV 0.96 0.95–0.97 0.96 0.94–0.97
 LR+ 22.4 9.2–31.5 35.1 14.8–83.3
 LR- 0.77 0.56–0.84 0.74 0.63–0.87
RSP0.7DSVC (n = 31)
 Sensitivity 0.22 0.11–0.36 0.21 0.11–0.34
 Specificity 0.99 0.98–1.00 0.99 0.98–1.00
 PPV 0.56 0.31–0.78 0.61 0.36–0.83
 NPV 0.96 0.95–0.97 0.96 0.94–0.97
 LR+ 25.4 10.6–61.5 27.6 11.1–68.3
 LR- 0.79 0.68–0.92 0.80 0.70–0.92

Definition of abbreviations: LLN Lower limit of normal; total lung capacity; PPV Positive predictive value, NPV Negative predictive value, LR+ Positive likelihood ratio, LR- Negative likelihood ratio, SVC Slow vital capacity