Bechelli 1985.
Methods | Allocation: randomised, stratified by Schizophrenia subgroups. Blindness: double. Duration: 6 months (preceded by 7 day washout). | |
Participants | Diagnosis: schizophrenia (RDC). History: >2 episodes, stabilized for 3 months, duration ill ‐ mean 12 yrs (HD) 9 yrs (PP), informed consent given. N = 41. Age: 19‐50 yrs (mean range 30‐33 yrs). Sex: all male. Race: caucasian. Setting: out‐patient clinic. | |
Interventions | 1. Haloperidol decanoate: dose mean 100mg/injection, monthly, range 50‐100mg/injection. N=21. 2. Pipothiazine palmitate: dose mean 75 (**65)mg/ injection, monthly, range 50‐ 125mg/injection. N=20. | |
Outcomes | Mental state (BPRS).
Leaving the study early.
Additional medication.
Side effects (Bordeleau Scale/AIMS). Unable to use ‐ Global Impression (CGI ‐ no data). Weight measures (non‐clinical outcomes, data not usuable). |
|
Notes | * Spitzer 1997 ** The mean dose of PP is given as 75mg in the abstract and 65mg in the paper. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment? | Unclear risk | B ‐ Unclear |