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. 1999 Jan 25;1999(1):CD001361. doi: 10.1002/14651858.CD001361

Chouinard 1984.

Methods Allocation: randomised, stratified by sex & past frequency of depot administration. 
 Blindness: double. 
 Duration: 8 months. 
 Statistics: last observation carried forward.
Participants Diagnosis: schizophrenia (DSM III). 
 History: on depot >3 months, duration ill ‐ mean 16 yrs, range 3‐38, informed consent given. 
 N=72. 
 Age: mean 44 yrs, range 18‐66. 
 Sex: 36 M, 36 F. 
 Setting: community.
Interventions 1. Haloperidol decanoate: dose mean 225mg/injection, 2‐4 weekly, range 15‐900mg/injection. N=36. 
 2. Fluphenazine decanoate: dose mean 75mg/injection, 2‐4 weekly, range 2.5‐300mg/injection. N=36.
Outcomes Global Impression (CGI). 
 Mental state (BPRS). 
 Leaving the study early. 
 Additional medication.
Unable to use ‐ 
 Side effects (ESRS ‐ authors own scale*, TESF ‐ no data reported). 
 Physiological measures (prolactin, drug plasma levels ‐ non clinical outcomes, data not usable).
Notes * Marshall et al, 1998.
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Unclear risk B ‐ Unclear