Eklund 1991.
Methods | Allocation: randomised. Blindness: double. Duration: 48 weeks (preceded by 15 week single blind 60mg HD/ month). | |
Participants | Diagnosis: schizophrenia (RDC). N=56 Age: mean ˜ 52 yrs (SD ˜ 12), range 25‐65. Sex: 37 F, 19 M. Setting: 37 community, 19 hospital. | |
Interventions | 1. Haloperidol decanoate: dose mean 60mg/ injection (fixed dose regimen), every 4 weeks. N=18/N=20* 2. Placebo: N=23 | |
Outcomes | Leaving the study early. Unable to use ‐ Additional medication (>30% attrition) Relapse (>30% attrition). Side effects (EPSS ‐ >30% attrition). Mental state (CPRS ‐ no SD). Physiological measures (plasma levels). |
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Notes | * N in HD group in abstract differs from N in paper. Authors contacted ‐ no reply. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment? | Unclear risk | B ‐ Unclear |