Kissling 1985.

Methods	Allocation: randomised, flip of a coin. Blindness: double. Duration: 6 months. Statistics: last observation carried forward.
Participants	Diagnosis: schizophrenia/ schizoaffective psychosis (DSM III). History: on oral medication, need depot treatment for >6 months, informed consent given. N=54. Age: ˜ 30 years (SD ˜11). Sex: 24 M, 7 F.
Interventions	1. Haloperidol decanoate: dose mean 80mg/ injection (actual dose given 50mg), monthly. N=32. 2. Fluphenazine decanoate: dose mean 21mg/ injection (actual dose given 25mg), every 2 weeks. N=22.
Outcomes	Leaving the study early. Unable to use ‐ Mental state (BPRS).* Additional medication (anticholinergics).* Side effects (EPMS, DOTES, STESS).* Physiological Measures (serum levels ‐ non clinical outcomes, data not usable).*
Notes	*The drop out rate after 6 months for FD=60%, HD=30%.
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment?	Unclear risk	B ‐ Unclear