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. 1999 Jan 25;1999(1):CD001361. doi: 10.1002/14651858.CD001361

McKane 1987.

Methods Allocation: randomised. 
 Blindness: double. 
 Duration: 60 weeks (preceded by 12 week 'run in' period where additional medication allowed).
Participants Diagnosis: schizophrenia (Fiegner criteria*). 
 History: on antipsychotics, duration ill ‐ mean 31 yrs, range 10‐50, next of kin gave consent. 
 N=38. 
 Age: mean 56 yrs, range 31‐ 71. 
 Sex : 22 M, 16 F. 
 Setting: in hospital.
Interventions 1. Haloperidol decanaote: initial dose mean 127 mg/injection, week 12 dose mean 120mg/ injection, monthly. N=17. 
 2. Fluphenazine decanoate: initial mean dose 106mg/ injection, week 12 dose mean 105/ injection, monthly. N=16.
Outcomes Mental state (Krawiecka scale). 
 Leaving the study early. 
 Additional medication. 
 Side effects (AIMS). 
 Parkinsonism (Simpson & Angus). 
 Behaviour (Wing Ward Behaviour Scale).
Unable to use ‐ 
 Global impresson (Global 5‐point scale ‐ no data). 
 Physiological measures (prolactin, drug plasma levels ‐ non clinical outcomes, data not usable).
Notes * Fiegner 1972
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Unclear risk B ‐ Unclear