Wistedt 1984.
Methods | Allocation: randomisation list, blocks of six. Blindness: double. Duration: 20 weeks. | |
Participants | Diagnosis: schizophrenia (RDC). History: duration ill ‐ range 0‐12 yrs, informed consent given. N=51. Age range: 21‐63 yrs. Sex: 33 M, 18 F. Setting: 4 weeks in hospital, community thereafter, multicentre. | |
Interventions | 1. Haloperidol decanoate: dose mean 122mg/injection, monthly. N=25. 2. Fluphenazine decanoate: dose mean 84mg/injection, monthly. N=26.* | |
Outcomes | Global impression (CGI).
Mental state (CPRS).
Leaving the study early.
Additional medication.
Side effects (AIMS, EPS). Unable to use ‐ Physiological measures (drug plasma levels ‐ non‐clinical outcomes, data not usable). Weight changes (non‐clincal outcomes, data not usable). |
|
Notes | Dose ratio :1:1.4 (FD/HD). | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment? | Unclear risk | B ‐ Unclear |