| Methods |
randomised , placebo‐controlled trial
double‐blind |
| Participants |
38 North American dependent parolees or probationers; mean age: 26 years; 68% unmarried; 5% completed the high school; all with criminal records with an average of 9 arrests. |
| Interventions |
naltrexone (19) versus placebo (19) ; outpatients.
naltrexone: six days a week for the first two months, then three times a week. Doses not specified
study duration: 9 month trial |
| Outcomes |
retention in treatment
use of substance (urine analysis) |
| Notes |
|
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Adequate sequence generation? |
Unclear risk |
method of sequence generation not described |
| Allocation concealment? |
Unclear risk |
method for allocation concealment not described |
| Blinding?
objective outcomes |
Low risk |
double blind |
| Blinding?
subjective outcomes |
Low risk |
double blind |
| Incomplete outcome data addressed?
All outcomes |
Low risk |
number of subject who withdrawn from the study and reason reported for each group |
