TABLE 3.

Clinicopathologic factors stratified by tumor size associated with survival after resection

	<1cm		1-1.99 cm		≥ 2 cm
Variable	HR (95% CI)	P value	HR (95% CI)	P value	HR (95% CI)	P value
Type of resection
LR	Reference		Reference		Reference
AR	1.02 (0.79-1.31)	.87	0.85 (0.58-1.23)	.39	1.02 (0.60-1.73)	.95
LN retrieval
No	Reference		Reference		Reference
Yes	1.13 (0.84-1.52)	.43	1.03 (0.69-1.53)	.89	0.85 (0.53-1.36)	.49
LN status
Negative	Reference		Reference		Reference
Positive	0.80 (0.43-1.48)	.48	1.13 (0.58-2.18)	.72	0.81 (0.43-1.51)	.50
Margin status
Negative	Reference		Reference		Reference
Positive	1.17 (0.81-1.69)	.39	1.57 (0.94-2.62)	.084	0.74 (0.32-1.71)	.48

Note: For multivariable analysis, backward selection with an α level of removal of 0.2 was used. Estimated stratified treatment effect was controlled by the following: age at diagnosis, sex, race, Charlson-Deyo score, and tumor grade

Abbreviations: AR, anatomic resection; CI, confidence interval; HR, hazard ratio; LR, local resection.

Bold indicates statistical significance.