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. 2020 Mar;26(3):549–559. doi: 10.3201/eid2603.191230

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Timeline showing antimicrobial drug exposure and plasmid changes in 3 carbapenem-resistant hypervirulent Klebsiella pneumoniae isolates from patient A2, Singapore, 2013–2014. pMDR646 contains genes aac(6’)-lb-cr,bla_OXA-1, qnrB1, catB3, and dfrA14. pMDR1734 contains genes aac(6’)-lb-cr, bla_OXA-1, and catB3. pKPC2 contains genes bla_KPC-2, bla_TEM-1A, bla_TEM-1B, and mph(A). KPC, Klebsiella pneumoniae carbapenemase; KPVP, Klebsiella pneumoniae virulence plasmid; MDR, multidrug resistance.