Table 1. Classifications and virulence characteristics of 18 carbapenem-resistant Klebsiella pneumoniae isolates harboring KPVP-associated genes, Singapore, 2013–2015*.
| Isolate | Patient no. | K locus | ST | Virulence score | Locus |
|||||
|---|---|---|---|---|---|---|---|---|---|---|
| Yersiniabactin | Colibactin | Aerobactin | Salmochelin | rmpA | rmpA2 | |||||
| ENT494 | A2 | 1 | 23 | 5 | ybt 1, ICEKP10 | clb 2 | iuc 1 | iro 1 | 2(KPVP-1) | 6 |
| ENT646 | A2 | 1 | 23 | 5 | ybt 1, ICEKP10 | clb 2 | iuc 1 | iro 1 | 2(KPVP-1) | 6 |
| ENT1734 | A2 | 1 | 23 | 5 | ybt 1, ICEKP10 | clb 2 | iuc 1 | iro 1 | 2(KPVP-1) | 6 |
| ENT1061 | A4 | 1 | 23 | 5 | ybt 1, ICEKP10 | clb 2 | iuc 1 | iro 1 | 2(KPVP-1) | 6 |
| ENT1256 | A6 | 1 | 23 | 5 | ybt 1, ICEKP10 | clb 2 | iuc 1 | iro 1 | 2(KPVP-1) | 5 |
| ENT1332 | A8 | 20 | 893 | 4 | ybt unknown | – | iuc 1 | iro 1 | 1(KPVP-1) | 2 |
| ENT1381 | A12 | 20 | 420 | 4 | ybt 9, ICEKP3 | – | iuc 1 | iro 1 | 1(KPVP-1) | 5 |
| ENT1192 | A14 | 2 | 86 | 4 | ybt 9, ICEKP3 | – | iuc 1 | iro 1 | 2(KPVP-1) | 6 |
| ENT1988 | A14 | 2 | 86 | 4 | ybt 9, ICEKP3 | – | iuc 1 | iro 1 | 2(KPVP-1) | 6 |
| ENT596 | A15 | 2 | 65 | 5 | ybt 17, ICEKP10 | clb 3 | iuc 1 | iro 1 | 2(KPVP-1) | 6 |
| ENT607 | A15 | 2 | 65 | 5 | ybt 17, ICEKP10 | clb 3 | iuc 1 | iro 1 | 2(KPVP-1) | 6 |
| ENT686 | A15 | 2 | 65 | 5 | ybt 17, ICEKP10 | clb 3 | iuc 1 | iro 1 | 2(KPVP-1) | 6 |
| ENT715 | A15 | 2 | 65 | 5 | ybt 17, ICEKP10 | clb 3 | iuc 1 | iro 1 | 2(KPVP-1) | 6 |
| ENT750 | A15 | 2 | 65 | 5 | ybt 17, ICEKP10 | clb 3 | iuc 1 | iro 1 | 2(KPVP-1) | 6 |
| ENT758 | A15 | 2 | 65 | 5 | ybt 17, ICEKP10 | clb 3 | iuc 1 | iro 1 | 2(KPVP-1) | 6 |
| ENT883 | A15 | 2 | 65 | 5 | ybt 17, ICEKP10 | clb 3 | iuc 1 | iro 1 | 2(KPVP-1) | 6 |
| ENT1072 | A15 | 2 | 65 | 5 | ybt 17, ICEKP10 | clb 3 | iuc 1 | iro 1 | 2(KPVP-1) | 6 |
| ENT1077 | A15 | 2 | 65 | 5 | ybt 17, ICEKP10 | clb 3 | iuc 1 | iro 1 | 2(KPVP-1) | 6 |
| ENT495† | 66 | 841 | 0 | – | – | – | – | – | – | |
| SGH10‡ | 1 | 23 | 5 | ybt 1, ICEKP10 | clb 2 | iuc 1 | iro 1 | 2(KPVP-1) | 6 | |
| CG43§ | 2 | 86 | 3 | – | – | iuc 1 | iro 1 | 1(KPVP-1) | 1 | |
*ICEKP, integrative conjugative element K. pneumoniae; KPVP, K. pneumoniae virulence plasmid; ST, sequence type. †Control carbapenem-resistant K. pneumoniae isolate (classified as K. quasipneumoniae by GenBank). ‡GenBank accession nos. CP025080 and CP025081. §GenBank accession nos. CP006648 and AY378100.