| 1 Treatment‐related outcomes: Bicarbonate |
3 |
|
Mean Difference (IV, Random, 95% CI) |
Subtotals only |
| 1.1 Venous bicarbonate |
3 |
106 |
Mean Difference (IV, Random, 95% CI) |
4.63 [1.06, 8.20] |
| 2 Treatment‐related outcpmes: Sodium |
1 |
|
Mean Difference (IV, Random, 95% CI) |
Totals not selected |
| 2.1 Sodium |
1 |
|
Mean Difference (IV, Random, 95% CI) |
0.0 [0.0, 0.0] |
| 3 Treatment‐related outcomes: Blood pressure |
1 |
|
Mean Difference (IV, Random, 95% CI) |
Totals not selected |
| 3.1 Systolic blood pressure mm Hg |
1 |
|
Mean Difference (IV, Random, 95% CI) |
0.0 [0.0, 0.0] |
| 3.2 Diastolic blood pressure mm Hg |
1 |
|
Mean Difference (IV, Random, 95% CI) |
0.0 [0.0, 0.0] |
| 4 Treatment‐related outcomes: Kt/V |
2 |
|
Mean Difference (IV, Random, 95% CI) |
Subtotals only |
| 4.1 Kt/V |
2 |
85 |
Mean Difference (IV, Random, 95% CI) |
‐0.07 [‐0.20, 0.07] |
| 5 Nutritional outcomes |
2 |
|
Mean Difference (IV, Random, 95% CI) |
Subtotals only |
| 5.1 Subjective global assessment (SGA) at 12 months |
1 |
53 |
Mean Difference (IV, Random, 95% CI) |
0.61 [0.07, 1.15] |
| 5.2 Normalized protein nitrogen appearance (NPNA) at 12 months |
1 |
53 |
Mean Difference (IV, Random, 95% CI) |
0.21 [0.07, 0.35] |
| 5.3 Protein catabolic rate (PCR) |
1 |
32 |
Mean Difference (IV, Random, 95% CI) |
0.08 [‐0.08, 0.24] |
| 5.4 Albumin |
2 |
85 |
Mean Difference (IV, Random, 95% CI) |
2.23 [‐2.71, 7.17] |
| 5.5 Oedema |
1 |
53 |
Mean Difference (IV, Random, 95% CI) |
‐0.29 [‐0.75, 0.17] |
| 5.6 Fat‐free oedema‐free body mass |
1 |
53 |
Mean Difference (IV, Random, 95% CI) |
2.80 [‐0.82, 6.42] |
| 5.7 Lean body mass |
1 |
53 |
Mean Difference (IV, Random, 95% CI) |
0.70 [‐4.20, 5.60] |
| 6 Bone metabolism outcomes: Phosphorus, osteocalcin and calcium |
2 |
|
Mean Difference (IV, Random, 95% CI) |
Subtotals only |
| 6.1 Phosphorus |
1 |
21 |
Mean Difference (IV, Random, 95% CI) |
‐0.90 [‐2.22, 0.42] |
| 6.2 Pre‐dialysis calcium (mg/dL) |
2 |
53 |
Mean Difference (IV, Random, 95% CI) |
‐0.18 [‐0.55, 0.19] |
| 6.3 Osteocalcin (ng/mL) |
2 |
23 |
Mean Difference (IV, Random, 95% CI) |
‐25.0 [‐76.93, 26.93] |
| 7 Bone metabolism outcomes: PTH |
2 |
|
Mean Difference (IV, Random, 95% CI) |
Subtotals only |
| 7.1 PTH (1‐84 pg/mL) |
2 |
53 |
Mean Difference (IV, Random, 95% CI) |
‐74.99 [‐207.55, 57.57] |
| 7.2 PTH (53‐84 pg/mL) |
1 |
21 |
Mean Difference (IV, Random, 95% CI) |
‐38.0 [‐250.90, 174.90] |
| 7.3 PTH (44‐68 pg/mL) |
1 |
21 |
Mean Difference (IV, Random, 95% CI) |
‐1872.00 [‐5486.99, 1742.99] |
| 8 Bone metabolism outcomes: Volume, surfaces, number and formation |
1 |
|
Mean Difference (IV, Random, 95% CI) |
Totals not selected |
| 8.1 Bone volume (%) |
1 |
|
Mean Difference (IV, Random, 95% CI) |
0.0 [0.0, 0.0] |
| 8.2 Osteoid volume (%) |
1 |
|
Mean Difference (IV, Random, 95% CI) |
0.0 [0.0, 0.0] |
| 8.3 Osteoid surfaces (%) |
1 |
|
Mean Difference (IV, Random, 95% CI) |
0.0 [0.0, 0.0] |
| 8.4 Osteoblast surfaces (%) |
1 |
|
Mean Difference (IV, Random, 95% CI) |
0.0 [0.0, 0.0] |
| 8.5 Osteoclast surfaces (%) |
1 |
|
Mean Difference (IV, Random, 95% CI) |
0.0 [0.0, 0.0] |
| 8.6 Osetoclasts/sq mm |
1 |
|
Mean Difference (IV, Random, 95% CI) |
0.0 [0.0, 0.0] |
| 8.7 Bone formation rate (cubic um/sq um/d) |
1 |
|
Mean Difference (IV, Random, 95% CI) |
0.0 [0.0, 0.0] |
| 8.8 Osteoid thickness (um) |
1 |
|
Mean Difference (IV, Random, 95% CI) |
0.0 [0.0, 0.0] |
| 9 Clinical outcomes: All‐cause mortality, hosptalisation |
1 |
|
Risk Ratio (M‐H, Random, 95% CI) |
Totals not selected |
| 9.1 Hospitalisation |
1 |
|
Risk Ratio (M‐H, Random, 95% CI) |
0.0 [0.0, 0.0] |
| 9.2 All‐cause mortality |
1 |
|
Risk Ratio (M‐H, Random, 95% CI) |
0.0 [0.0, 0.0] |
| 10 Clinical outcomes: Hospital admissions/patient, length of hospital stay |
1 |
|
Mean Difference (IV, Random, 95% CI) |
Totals not selected |
| 10.1 Hospital admissions/patient |
1 |
|
Mean Difference (IV, Random, 95% CI) |
0.0 [0.0, 0.0] |
| 10.2 Average length of hospital stay |
1 |
|
Mean Difference (IV, Random, 95% CI) |
0.0 [0.0, 0.0] |
