Table 3.
Ten DMGs associated with immunity or reproduction.
| Gene ID | Gene Name | KEGG pathway | GO term |
|---|---|---|---|
| ENSSSCG00000007520 | GNAS | Ovarian steroidogenesis, Oxytocin signaling pathway, Estrogen signaling pathway, GnRH signaling pathway | post-embryonic body morphogenesis, embryonic hindlimb morphogenesis |
| ENSSSCG00000022126 | EGFR | Estrogen signaling pathway, GnRH signaling pathway, Oxytocin signaling pathway | Embryonic placenta development |
| ENSSSCG00000006374 | CD244 | Natural killer cell mediated cytotoxicity | natural killer cell activation involved in immune response, positive regulation of CD8-positive, α-β T cell proliferation, positive regulation of interferon-γ secretion, positive regulation of interleukin-8 secretion. |
| ENSSSCG00000006736 | CD2 | positive regulation of interferon-γ secretion, positive regulation of interleukin-8 secretion | |
| ENSSSCG00000021576 | CD83 | negative regulation of interleukin-4 production, interferon-γ secretion, positive regulation of CD4-positive, alpha-β T cell differentiation, positive regulation of interleukin-10 production, humoral immune response | |
| ENSSSCG00000013115 | CD5 | T cell costimulation | |
| ENSSSCG00000040183 | CDK6 | response to virus, T cell differentiation in thymus, type B pancreatic cell development, T cell differentiation in thymus, response to virus | |
| ENSSSCG00000000555 | ITPR2 | Oocyte meiosis, Oxytocin signaling pathway, Estrogen signaling pathway, GnRH signaling pathway | |
| ENSSSCG00000011141 | CALML5 | Oocyte meiosis, Oxytocin signaling pathway, Estrogen signaling pathway, GnRH signaling pathway | |
| ENSSSCG00000021828 | TAPT1 | embryonic skeletal system development, post-embryonic development, in utero embryonic development |
Genes that found within the DMRs or closest to the DMRs of the intergenic region were defined as DMGs to perform KEGG pathway enrichment analysis and gene function enrichment analysis via GO.