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. 2020 Jan 23;12(2):3832–3849. doi: 10.1093/gbe/evaa008

Table 3.

Overview of Great Gerbil MHCII Genes and Their Location in the Genome Assembly

Gene Scaffold Strand Start End Size (aa) Full-Length Coding Sequence
Rhop-DPB scaffold00896 116,069 105,406 264 Yes
Rhop-DPA scaffold00896 + 117,514 120,092 252 Yes
Rhop-DOA scaffold00896 + 125,319 127,406 241 Yesa
Rhop-DMa scaffold00896 + 166,162 168,926 265 Yesb
Rhop-DMb scaffold00896 + 175,763 182,090 257 Yes
Rhop-DOB scaffold00896 + 239,915 245,006 172 Noc
Rhop-DQB scaffold00896 + 271,007 278,482 231 Nod
Rhop-DQA scaffold00896 294,074 290,301 255 Yes
Rhop-DRB1 scaffold00896 + 310,644 319,368 265 Yes
Rhop-DRB2 scaffold00896 + 326,384 347,931 272 Yese
Rhop-DRA scaffold00896 355,351 351,425 254 Yes
Rhop-DRB3 scaffold00896 403,768 395,068 265 Yes

note.—The table details the assigned great gerbil gene names, which scaffold and in what orientation they are located as well as genomic location on the scaffold for start and end of the genes. Information on the size of the translated amino acid sequence and whether it is complete is also shown. In addition, see supplementary figure S7, Supplementary Material online.

a

Missing final residue and stop codon due to conserved overlapping splice site.

b

Unable to locate a stop codon. The structure of the final two exons is conserved among human, mouse, and rat with the ultimate residue overlapping the splice site. The final coding exon therefore only contains 2 bp and the stop codon making it hard to determine the location of the final exon in the gerbil without supporting RNA information.

c

Missing 99 residues (121–219) due to assembly gap.

d

Start location is that of exon 2 as exon 1 is missing due to an assembly gap.

e

The cytoplasmic tail of β2 genes are encoded by an exon with no known homology to other exons in the MHCII genes and has a low degree of homology between mouse and rat (Monzón-Casanova et al. 2016). There is therefore some uncertainty related to the completeness of the final exon of Rhop-DRB2.