Table 4.

Areas in which existing standards overlap with the time concept

Proposed concept	Relevant HL7 FHIR resources	Relevant CDISC PRM/SDTM/SDTMIG-MD domains	Relevant W3C SOSA and SSNO modules	Relevant Open mHealth schemas
Time	Encompasses timing variables within each of the above resources	Encompasses timing variables within each of the above domains	Encompasses timing variables within the observation and result module	Date Time interval Part of day Patient medication schedule Temporal relationship to meal Temporal relationship to physical activity Temporal relationship to sleep

CDISC, Clinical Data Interchange Standards Consortium; FHIR, Fast Healthcare Interoperable Resources; HL7, Health Level 7; PRM, Protocol Representation Model; SDTM, Study Data Tabulation Model; SDTMIG-MD, Study Data Tabulation Model Implementation Guide for Medical Devices; SOSA, Sensor, Observation, Sample, and Actuator; SSNO, Semantic Sensor Network Ontology.