Fig 6. Type-I interferon signalling is necessary to enhance vomocytosis.

Human monocyte-derived macrophages were infected with HIV (A) or GFP-expressing measles virus (MeV-GFP, B) and subsequently with mCherry-expressing C. neoformans (Kn99α-mCherry), in the presence or absence of an IFNAR blocking antibody. GFP negative cells, which did not have an active Measles infection, were termed “Non-MeV”. Graph shows Mean + SD of percentage of Cryptococcus-infected macrophages which have experienced at least one vomocytosis event. Fisher's exact test performed on raw vomocytosis counts. Pooled data from two and three biological repeats, respectively.