Fig 5. Basal CYP3A4 and PXR expression in differentiating human iPSCs.
(A) Human induced pluripotent stem cells are differentiated into hepatocyte like cells via a 25-day long protocol. Representative pictures of cells at different differentiation stages are presented. (B) The basal expression levels of CYP3A4 and PXR were quantified at different differentiation stages and are normalized against undifferentiated iPSC cells. The data are presented as mean ± SEM, N = 6.