Table 2. Feed intake (g/day per pen), BW (Kg), average daily gain (g/day) and feed efficiency (g/g per pen) from days 0‒7, 8‒14, and 0‒14 post-infection of piglets.

Salicylatea	SA-		SA+		SEM	P-valuese
Chestnut extractb	CE-	CE+	CE-	CE+		SA	CE	T
Body weight (kg)c
At day 0d	7.30	7.53	7.26	7.31	0.365	0.36	0.10	< 0.001
At day 7	8.01	8.57	7.76	8.18
At day 14	9.67	10.47	9.37	10.14
Feed intake per pen (g/day)
Days 0‒7	415	488	353	458	61.7	0.22	0.02	< 0.001
Days 8‒14	827	979	811	887
Days 0‒14	635	716	546	720	53.6	0.42	0.02	-
Average daily gain (g/day)
Days 0‒7	101	149	70	124	21.5	0.35	0.004	< 0.001
Days 8‒14	238	273	230	280
Days 0‒14	169	210	150	202	22.5	0.52	0.04	-
Gain-to-feed per pen (g/g)
Days 0‒7	0.52	0.60	0.28	0.51	0.111	0.22	0.35	0.11
Days 8‒14	0.62	0.59	0.59	0.59
Days 0‒14	0.55	0.59	0.55	0.56	0.039	0.62	0.59	-

^a SA+: From days 0‒4, pigs (N = 36) were offered a daily dose of sodium salicylate (35 mg/kg BW per day; sodium salicylate, ReagentPlus®, S3007, Sigma-Aldrich Chemie GmbH; Buchs, Switzerland). SA-: From days 0‒4, pigs (N = 36) were offered a daily dose of tap water.

^b CE-: Pigs (N = 36) had ad libitum access to the control standard starter diet, which was formulated according to the Swiss feeding recommendations for pigs (Agroscope, 2017). CE+: Pigs (N = 36) had ad libitum access to the chestnut extract (CE)-supplemented diet, in which wheat straw in the CE- diet was substituted for with 2% CE (Silvafeed Nutri P/ENC for Swine; Italy).

^c Significant D × T interaction for body weight (P = 0.001).

^d Body weights at weaning and at day 0 did not (P> 0.10) differ between the four experimental groups.

^e P-values for the main effect of salicylate supply (SA), chestnut extract supplementation (CE) and time (T).