TABLE 5.
Percentages of Bulbospinal Neurons with GABAA Subunit-Immunoreactivity
| RVLM (FN-5 to FN-1) | RVLMre (FN0 to FN+4) | |||
|---|---|---|---|---|
| Bulbospinal C1 = CTB+ / TH+ | Active | Sedentary | Active | Sedentary |
| GABAAα1+ (n = 8/9)a,b | 55±4% | 66±3%* | 45±3%# | 49±3%#* |
| GABAAα2+ (n = 10/10)c,d | 76±2% | 80±3% | 58±2%# | 61±3%# |
| Bulbospinal non-C1 = CTB+ / TH− | Active | Sedentary | Active | Sedentary |
| GABAAα1+ (n = 8/9)e,f | 29±3% | 20±2%p=0.06 | 43±3%# | 41±4%#;p=0.06 |
| GABAAα2+ (n = 10/10)g,h | 18±2% | 12±3% | 37±2%# | 32±4%# |
Data presented as mean ± SEM; 2-way mixed ANOVA for all comparisons (see p and f values below).
C1/GABAAα1+
a
*, F1,15 = 5.3; p=0.037; Active vs Sedentary;
b
#, F1,15 = 21.2; p<0.001, RVLM vs RVLMRE; Intxn: F 1,15 = 1.54, p=0.23
C1/GABAAα2+
c
F1,15 = 0.9; p=0.35; Active vs Sedentary;
d
#, F1,15 = 81.9; p<0.001; RVLM vs RVLMRE; Intxn: F1,15 = 0.00003, p=0.99
non-C1/GABAAα1+
e
F1,15 = 4.1; p=0.06; Active vs Sedentary;
f
#, F1,15 = 36.7; p<0.001; RVLM vs RVLMRE; Intxn: F1,15 = 1.45, p=0.25
non-C1/GABAAα2+
g
F1,15 = 2.3; p=0.146; Active vs Sedentary;
h
#, F1,15 = 27.4; p<0.001; RVLM vs RVLMRE; Intxn: F1,15 = 0.24, p= p=0.63