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LncAIS interacts with NF90, stabilizing the HOXD8 mRNA and further enhances the transcription of RUNX2, which alters the osteogenic differentiation process of BM-MSCs. BM-MSCs: Bone marrow-derived mesenchymal stem cells; HOXD8: Homeobox D8; LncAIS: Long non-coding AIS (gene symbol: ENST00000453347); NF90: Nuclear factor 90; RUNX2: Runt-Related transcription factor 2.
