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. 2020 Jan 19;53(2):e12738. doi: 10.1111/cpr.12738

Figure 8.

Figure 8

SPAG5‐AS1/miR‐769‐5p/YY1‐positive feedback loop transcriptionally induced SPAG5 and SPAG5‐AS1 interacted with USP14 to induce de‐ubiquitination of SPAG5, so that AKT/mTOR signalling was activated to inhibit autophagy and induce apoptosis in podocytes