Table 1.

OX40-targeted drugs

Type	Drug
Humanised IgG1 agonist mAb	ABBV-368
	GSK3174998
	MEDI0562
	MOXR0916 (vonlerolizumab)
Fully human IgG1 agonist mAb	INCAGN01949
	IBI101
	BMS-986178
Fully human IgG2 agonist Ab	PF-04518600
Murine IgG1 agonist mAb	MEDI6469P
	9B12
Human IgG1 CTLA-4 × OX40 bispecific Ab	ATOR-1015
Lipid nanoparticle encapsulating mRNAs encoding human OX40L, IL-23 and IL-36γ	mRNA-2752
Human OX40L IgG4P Fc fusion protein	MEDI6383
Dual-sided Fc fusion protein PD1-Fc-OX40L	SL-279252

Ab, antibodies; IL, interleukin; mAb, monoclonal antibodies.