Cognitive moderation effects on the development of putamen R2* across subdomains of cognition. Fitted values of R2* are plotted as functions of age and complex cognition (A), social cognition (B), executive function (C), and memory (D). To visualize the continuous interactions, fitted lines are displayed that depict the relationship between age and putamen R2* for the top 5% (High performers) and bottom 95% (Low performers) of the range for each cognitive measure. Individual points represent individual scans, with connecting lines indicating scans from the same participant. The color of the points represents the cognitive z score (higher values indicating more efficient performance).