Figure 2.

SGLT2 Inhibition Promotes Glucosuria and Decreases Weight Gain in Hypertensive BPH/2J Mice

(A) Representative image of glucose levels in the urine after 10 days of dapagliflozin (40 mg/kg) treatment (yellow = 0 mmol/l glucose, blue = 278 mmol/l glucose). (B) Increase in body weight of mice after 2 weeks of dapagliflozin (DAPA) treatment (starting at week 0), n = 6 to 8 mice/group. *p < 0.05; data presented as mean ± SEM. Abbreviation as in Figure 1.