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. 2020 Feb 3;19:100248. doi: 10.1016/j.eclinm.2019.100248

Table 3.

Adjusted geometric means of risk factors across quintiles of total SAA intake.

Quintile of total SAA intake
P-Value
Risk factors Q1 Q2 Q3 Q4 Q5 Q5 vs Q1 Trend
Z Score −0.60 −0.27 −0.07 0.29 0.64 <0.01 <0.01
Serum cholesterol (mg/dL)
Unadjusted 203 (201–205) 204 (203–206) 204(203–206) 207 (205–209) 206 (205–208) 0.07 <0.01
Adjusted* 203 (201–205) 204 (203–206) 204 (203–206) 207 (205–209) 207 (205–208) 0.04 <0.01
Serum HDL cholesterol (mg/dL)
Unadjusted 52.0 (51.4–52.6) 52.1 (51.4–52.7) 51.7 (51.0–52.3) 51.4 (50.8–52.0) 50.5 (49.8–51.1) <0.01 <0.01
Adjusted* 51.2 (50.5–51.8) 51.0 (50.4–51.6) 51.3 (50.7–51.9) 51.9 (51.3–52.4) 52.3 (51.7–52.9) 0.09 <0.01
Systolic pressure (mmHg)
Unadjusted 126 (124–127) 125 (124–127) 126 (125–127) 126 (125–126) 126 (125–128) 0.95 0.30
Adjusted* 125 (124–126) 126 (125–127) 127 (126–128) 126 (125–128) 125 (124–127) 0.99 0.77
Diastolic pressure (mmHg)
Unadjusted 75.0 (73.6–76.3) 75.1 (73.8–76.4) 75.8 (74.5–77.1) 76.1 (74.8–77.4) 75.4 (74.1–76.7) 0.99 0.49
Adjusted* 74.6 (73.2–6.0) 75.6 (74.3–76.9) 76.3 (75.0–77.7) 76.1 (74.8–77.4) 74.7 (73.3–76.1) 1.00 1.00
Serum glucose (mg/dL)
Unadjusted 95.9 (94.5–97.2) 96.8 (95.4–98.2) 98.1 (96.7–99.5) 101 (99.9–103) 103 (102- 105) <0.01 <0.01
Adjusted* 97.6 (96.3–98.8) 99.1 (97.9–100) 99.0 (97.8–100) 99.5 (98.3- 101) 100 (99.1- 102) 0.05 <0.01
Serum triglycerides (mg/dL)
Unadjusted 137(133–141) 137 (132–141) 136 (132–141) 142(138–147) 150(145–154) <0.01 <0.01
Adjusted* 139 (135–144) 141 (137–146) 139 (135–143) 140 (136–145) 142 (137–146) 0.95 0.28
Glycated hemoglobin (%)
Unadjusted 5.39 (5.34–5.43) 5.41 (5.36–5.45) 5.50 (5.46–5.54) 5.57 (5.53–5.61) 5.67 (5.62–5.71) <0.01 <0.01
Adjusted* 5.45 (5.41–5.49) 5.47 (5.43–5.51) 5.53 (5.49–5.56) 5.51 (5.48–5.55) 5.57 (5.54–5.61) <0.01 <0.01
Serum C-reactive protein (mg/dL)
Unadjusted 0.42 (0.39–0.45) 0.45 (0.43–0.48) 0.48 (0.45–0.51) 0.45 (0.42–0.48) 0.46 (0.43–0.49) 0.43 0.16
Adjusted* 0.44 (0.40–0.47) 0.45 (0.42–0.48) 0.47 (0.44–0.50) 0.44 (0.41–0.47) 0.48 (0.45–0.51) 0.37 0.11
Serum uric acid (mg/dL)
Unadjusted 5.27 (5.21–5.33) 5.15 (5.10–5.21) 5.14 (5.08–5.20) 5.32 (5.26–5.38) 5.51 (5.45–5.56) <0.01 <0.01
Adjusted* 5.17 (5.11–5.22) 5.27 (5.23–5.32) 5.24 (5.19–5.29) 5.34 (5.29–5.39) 5.37 (5.32–5.42) <0.01 <0.01
BUN (mg/dL)
Unadjusted 13.1 (12.9–13.3) 13.6 (13.4–13.8) 14.1 (14.0–14.4) 14.7 (14.5–14.9) 15.5 (15.3–15.7) <0.01 <0.01
Adjusted* 13.1 (12.9–13.3) 13.7 (13.6–13.9) 14.3 (14.1–14.5) 14.7 (14.5–14.9) 15.3 (15.1–15.5) <0.01 <0.01
Serum insulin (μU/mL)
Unadjusted 10.5 (9.4–11.6) 11.9 (10.8–13.0) 11.6 (10.5–12.7) 13.1 (12.0–14.2) 14.3 (13.2–15.4) <0.01 <0.01
Adjusted* 11.2 (10.1–12.4) 12.5 (11.4–13.6) 11.7 (11.6–12.8) 12.4 (11.3–13.5) 13.7 (12.5–14.8) 0.04 <0.01
eGFR
Unadjusted 69.2 (68.7–69.7) 69.8 (69.3–70.4) 69.9 (69.4–70.4) 70.0 (69.5–70.5) 69.8 (69.2–70.3) 0.57 0.18
Adjusted* 69.2 (68.6–69.7) 69.7 (69.2–70.3) 69.8 (69.3–70.3) 70.0 (69.4–70.5) 70.0 (69.4–70.5) 0.26 0.05

Note: adjusted for age (continuous), gender, total energy intake (kcal/day), smoking status (yes/no), alcohol intake (g/day) and BMI (categorical), total fat (g/day), calcium (mg/day), magnesium (mg/day), sodium (g/day), potassium (g/day), vitamin A (IU/day), vitamin C (mg/day), vitamin B6 (mg/day) folic acid (mcg/day) intake, diabetes, and hypertension history.