Fig. 2.

Apoptosis, etosis and proliferation rates in different stages of thrombus progression. Rates of apoptosis, etosis and proliferation were measured as a percentage of total number of immunopositive pixels of Casp3(A), CitH3(B) and Ki67(C), respectively, versus total number of Feulgen positive pixels in the selected region of interest in fresh (FR), lytic (LY), early (EO) and late organized (LO). The highest rates of etosis and apoptosis were found in lytic while the lowest in organized thrombi (*p < 0.05, significant to LO). In contrast, rate of proliferation was higher in organized than in fresh and lytic thrombi.