. 2020 Feb 5;5(2):183–192. doi: 10.1016/j.jacbts.2019.11.010

Table 1.

Hemodynamic Data at Baseline and at 5-Min Intervals During 30 Min of CPR

Time	Treatment	RA Pressure, mm Hg	Compression RA Pressure, mm Hg	SBP, mm Hg	DBP, mm Hg	CPP, mm Hg	%CBF
BL	SNPeCPR	5 ± 0.9	Not applicable	111 ± 17.0	76 ± 13.6	71 ± 12.7	100 ± 0
BL	Standard ACLS CPR	4 ± 0.4	Not applicable	107 ± 15.5	72 ± 13.0	68 ± 8.9	100 ± 0
5 min	SNPeCPR	7 ± 1.1	72 ± 8.9	73 ± 9.3	28 ± 6.5	21 ± 5.8	25 ± 5.5
5 min	Standard ACLS CPR	8 ± 2.3	65 ± 18.8	64 ± 19.7	26 ± 5.2	18 ± 5.8	24 ± 10.8
10 min^∗	SNPeCPR	6 ± 1.7	68 ± 10.5	69 ± 11.1	28 ± 5.1	22 ± 5.6	22 ± 4.5
10 min^∗	Standard ACLS CPR	8 ± 2.7	65 ± 22	64 ± 21.4	27 ± 10.0	19 ± 6.4	26 ± 12.1
15 min	SNPeCPR	7 ± 2.1	63 ± 10.8	64 ± 10.0	31 ± 9.2	24 ± 5.0^†	30 ± 10.0^†
15 min	Standard ACLS CPR	6 ± 1.6	69 ± 20.6	68 ± 21.4	25 ± 9.8	19 ± 7.1^†	23 ± 2.0^†
20 min	SNPeCPR	5 ± 2.9	61 ± 14.2	63 ± 13.7	30 ± 11.6	25 ± 6.0^†	30 ± 11.1^†
20 min	Standard ACLS CPR	6 ± 3.1	66 ± 20.9	67 ± 22.5	23 ± 10.2	17 ± 5.6^†	21 ± 4.4^†
25 min	SNPeCPR	6 ± 3.2	60 ± 18.2	59 ± 17.7	30 ± 11.1^†	24 ± 7.5^†	31 ± 14.1^†
25 min	Standard ACLS CPR	4 ± 1.8	58 ± 17.3	59 ± 17.6	20 ± 5.7^†	16 ± 6.1^†	17 ± 1.7^†
30 min	SNPeCPR	10 ± 6.5	59 ± 23.9	58 ± 25.2	30 ± 13.1^†	20 ± 11.7^†	24 ± 8.1^†
30 min	Standard ACLS CPR	3 ± 0.6	57 ± 17.8	56 ± 19.5	17 ± 5.2^†	14 ± 4.6^†	18 ± 3.1^†

Values are mean ± SEM.

ACLS = advanced cardiac life support; BL = baseline values; CBF = carotid blood flow; %CBF = proportion of CBF as a percent of the initial baseline value; CPP = coronary perfusion pressure; CPR = cardiopulmonary resuscitation; DBP = diastolic blood pressure; RA = right atrial; SBP = systolic blood pressure; SNPeCPR = sodium nitroprusside–enhanced cardiopulmonary resuscitation.

^∗

The dividing line at 10 min indicates the initiation of randomization and drug administration.

^†

p < 0.05.