Fig. 17.

Succinyl-lysine immunolabeling in the human cerebral cortex in relation to neuronal and glial markers. a Succinyl-lysine-immunoreactive (SUCCLYS-ir) cells are present in the cerebral cortex, with higher density in the deep layers. b Succinyl-lysine (green) and fluorescent Nissl staining (red) show that essentially all cells are double-labeled in the cerebral cortex. Arrows point to some of these double-labeled cells. Note the dot-like distribution of succinyl-lysine immunolabeling in the double-labeled cells. c A cerebral cortical section double labeled with succinyl-lysine (green) and the established astrocyte marker glial fibrillary acidic protein (GFAP; red) to show the double labeling of astrocytes. White arrowheads point to single-labeled (SUCCLYS-ir) neurons. Scale bars = 300 µm for a and 30 µm for b and c