Table 7.
Survival analysis: time to conversion to Dementia in patients with amnestic mild cognitive impairment at baseline.
| Variable name | Univariate | Multivariate | ||||
|---|---|---|---|---|---|---|
| Hazard Ratio | 95% CI | P | Hazard Ratio | 95% CI | P | |
| Age (year) | 1.06 | 1.02,1.10 | 0.002 | 1.039 | 0.99,1.09 | 0.12 |
| Gender (female) | 0.63 | 0.39,1.01 | 0.06 | 1.643 | 0.81,3.35 | 0.17 |
| ApoE E4 (present) | 0.94 | 0.56,1.56 | 0.80 | 0.539 | 0.23,1.24 | 0.15 |
| FCSRT-IR | 0.95 | 0.93,0.97 | <0.0001 | 0.957 | 0.92,0.99 | 0.02 |
| MOCA | 0.81 | 0.73,0.89 | <0.0001 | 0.833 | 0.71,0.98 | 0.03 |
| RLCQ | 0.99 | 0.99,1.00 | 0.31 | 0.999 | 0.99,1.00 | 0.40 |
| PSS | 0.98 | 0.95,1.02 | 0.31 | 1.027 | 0.98,1.08 | 0.29 |
| S1 | 0.57 | 0.37,0.87 | 0.01 | 0.539 | 0.26,1.14 | 0.10 |
| CAR | 1.50 | 0.88,2.44 | 0.14 | 0.792 | 0.35,1.77 | 0.57 |
| cortisol AUC | 1.00 | 0.99,1.00 | 0.95 | 1.004 | 1.00,1.01 | 0.06 |
MOCA = Montreal Cognitive Assessment; FCSRT-IR = Free and Cued Selective Reminding Test with immediate recall; RLCQ = Recent Life Changes Questionnaire; PSS = Perceived Stress Scale; S1 = Awakening cortisol sample; CAR = Cortisol awakening response; cortisol AUC = area under daytime cortisol curve; ApoE ε4 = Apolipoprotein E ε4 allele carrier.