Table 1.
Patient characteristics by mLOY status.
| Characteristics | Normal | mLOY | Pa |
|---|---|---|---|
| Participants | 166548 (80.7) | 39809 (19.3) | NA |
| Age (mean,SD) | 55.199 (8.168) | 61.882 (5.784) | <5 × 10−324 |
| Ethnicity | |||
| White | 155443 (80) | 38790 (20) | Ref |
| Mixed | 922 (90.5) | 97 (9.5) | <5 × 10−324 |
| Asian | 4932 (91.9) | 436 (8.1) | <5 × 10−324 |
| Black | 2914 (94.2) | 181 (5.8) | <5 × 10−324 |
| Other | 1648 (92.3) | 138 (7.7) | <5 × 10−324 |
| Smoking status | |||
| Never | 86007 (84.8) | 15474 (15.2) | Ref |
| Former | 60851 (77.8) | 17388 (22.2) | <5 × 10−324 |
| Current | 19072 (73.8) | 6770 (26.2) | <5 × 10−324 |
| Alcohol drinking | |||
| Never | 4877 (84.7) | 883 (15.3) | Ref |
| Former | 5660 (79.2) | 1487 (20.8) | 8.88 × 10−16 |
| Current | 155837 (80.6) | 37408 (19.4) | 4.00 × 10−15 |
| Body mass index | |||
| 18.5- | 339 (78.3) | 94 (21.7) | 0.279 |
| 18.5to25 | 39733 (80.4) | 9702 (19.6) | Ref |
| 25to30 | 80774 (80.3) | 19853 (19.7) | 0.636 |
| 30to35 | 32845 (81.4) | 7507 (18.6) | 1.08 × 10−4 |
| 35+ | 9864 (84.8) | 1767 (15.2) | <5 × 10−324 |
| Diseases | |||
| Diabetes | 9870 (79) | 2625 (21) | 6.71 × 10−7 |
| Hypertension | 48007 (77.4) | 14033 (22.6) | <5 × 10−324 |
| Hypercholesterolemia | 24396 (74.9) | 8192 (25.1) | <5 × 10−324 |
Abbreviations: mLOY: mosaic loss of the Y chromosome.
aFisher’s exact test with mid-p method.