Table 5.
Gene ontology and reactome pathway analyses for the enrichment of GO and reactome pathway terms in dairy and draft cattle.
| Term enriched | Number of genes in reference database (B. taurus) |
Observed number of genes |
Expected number of genes |
Fold enrichment |
+/- | False declaration rate (FDR) |
|---|---|---|---|---|---|---|
| Dairy cattle | ||||||
| GO term enriched | ||||||
| Panther GO-Slim Biological process | ||||||
| Mammary gland development | 5 | 3 | 0.10 | 31.41 | + | 2.08E-02 |
| Steroid metabolic process | 115 | 13 | 2.20 | 5.92 | + | 2.15E-04 |
| G-coupling receptor signaling pathway | 753 | 2 | 14.38 | 0.14 | - | 8.46E-03 |
| Panther GO Slim cellular component | ||||||
| Cell junction | 129 | 11 | 2.46 | 4.46 | + | 2.19E-03 |
| GO cellular component complete | ||||||
| Golgi lumen | 10 | 5 | 0.19 | 26.18 | + | 9.23E-04 |
| Draft cattle | ||||||
| GO term enriched | ||||||
| Panther GO SLIM biological process | ||||||
| G-coupling receptor signaling pathway | 753 | 7 | 24.59 | 0.28 | - | 1.28E-02 |
| Panther GO SLIM Cellular component | ||||||
| Microtubule | 145 | 13 | 4.74 | 2.75 | + | 2.52E-02 |
| Panther GO Molecular function complete | ||||||
| Catalytic activity acting on RNA | 363 | 30 | 11.85 | 2.53 | + | 4.91E-02 |
| Catalytic activity | 6041 | 252 | 197.27 | 1.28 | + | 2.50E-02 |
| Reactome pathway term enriched | ||||||
| Activation of the pre-replicative complex | 31 | 7 | 1.01 | 6.91 | + | 4.02E-02 |
| G2/M transition | 156 | 16 | 5.09 | 3.14 | + | 4.35E-02 |
FDR < 0.05; ‘+’: Over representation; ‘-’: Under representation.