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. 2020 Feb 27;10:3594. doi: 10.1038/s41598-020-60433-4

Figure 5.

Figure 5

Loss of AIF1L does not alter metabolic profile with short- or long-term HFD feeding. (a–c) Metabolic cage studies performed on WT (n = 3) and KO (n = 4) mice fed HFD for 6 weeks (a) Energy expenditure (EE). Bar graph represents average EE values during day, night, and total. (b) Respiratory exchange ratio (RER; VCO2/VO2). Bar graph represents average RER values during day, night, and total. (c) Physical activity measured as beam breaks (Counts). Bar graph represents average beam break counts values during day, night, and total. (d–f) Metabolic cage studies performed on WT (n = 3) and KO (n = 3) mice fed HFD for 18 weeks. (d) Energy expenditure (EE). Bar graph represents average EE values during day, night, and total. (e) Respiratory exchange ratio (RER; VCO2/VO2). Bar graph represents average RER values during day, night, and total. (f) Physical activity measured as beam breaks (Counts). Bar graph represents average beam break counts values during day, night, and total. Data are represented in mean ± SEM. ns – not significant.