Table 2.
Comparison of tumor characteristics between endometrial carcinoma patients with none versus any combination of leiomyomas, adenomyosis or endometriosis.
| Tumor Characteristic | None | Leiomyomas only | Adenomyosis only | Endometriosis only | Leiomyomas & Adenomyosis | Leiomyomas & Endometriosis | Adenomyosis & Endometriosis | All three conditions |
|---|---|---|---|---|---|---|---|---|
| aN (%) | aN (%) | aN (%) | aN (%) | aN (%) | aN (%) | aN (%) | aN (%) | |
| Subset of all cases (n = 1399) | 352 (25.2) | 385 (27.5) | 174 (12.4) | 37 (2.6) | 309 (22.1) | 53 (3.8) | 19 (1.4) | 70 (5.0) |
| Tumor Histology & Grade | ||||||||
| Endometrioid Grade 1 | 152 (43.2) | 185 (48.1) | 95 (54.6) | 18 (48.6) | 191 (61.8) | 25 (47.2) | 12 (63.2) | 47 (67.1) |
| Endometrioid Grade 2 | 89 (25.3) | 100 (26.0) | 51 (29.3) | 10 (27.0) | 67 (21.7) | 14 (26.4) | 5 (26.3) | 13 (18.6) |
| Endometrioid Grade 3 | 50 (14.2) | 35 (9.1) | 7 (4.0) | 4 (10.8) | 18 (5.8) | 3 (5.7) | 1 (5.3) | 2 (2.9) |
| Serous (>5%) | 33 (9.4) | 32 (8.3) | 11 (6.3) | 4 (10.8) | 19 (6.1) | 7 (13.2) | 1 (5.3) | 4 (5.7) |
| Clear Cell (>10%), no serous | 10 (2.8) | 14 (3.6) | 5 (2.9) | 0 (0.0) | 4 (1.3) | 2 (3.8) | 0 (0.0) | 0 (0.0) |
| Carcinosarcoma (MMMT) | 13 (3.7) | 18 (4.7) | 2 (1.1) | 0 (0.0) | 7 (2.3) | 0 (0.0) | 0 (0.0) | 4 (5.7) |
| bOther epithelial | 5 (1.4) | 1 (0.3) | 3 (1.7) | 1 (2.7) | 3 (1.0) | 2 (3.8) | 0 (0.0) | 0 (0.0) |
| FIGO stage | ||||||||
| I | 263 (75.8) | 311 (81.0) | 149 (85.6) | 29 (78.4) | 282 (91.3) | 42 (80.8) | 18 (94.7) | 62 (88.6) |
| II | 32 (9.2) | 31 (8.1) | 15 (8.6) | 1 (2.7) | 9 (2.9) | 4 (7.7) | 1 (5.3) | 5 (7.1) |
| III | 39 (11.2) | 35 (9.1) | 10 (5.7) | 6 (16.2) | 17 (5.5) | 5 (9.6) | 0 (0.0) | 2 (2.9) |
| IV | 13 (3.7) | 7 (1.8) | 0 (0.0) | 1 (2.7) | 1 (0.3) | 1 (1.9) | 0 (0.0) | 1 (1.4) |
| Lymphovascular Space Involvement | ||||||||
| No/Unknown | 259 (73.6) | 298 (75.1) | 148 (85.1) | 27 (73.0) | 261 (84.5) | 41 (77.4) | 17 (89.5) | 59 (84.3) |
| Yes | 93 (26.4) | 96 (24.9) | 26 (14.9) | 10 (27.0) | 48 (15.5) | 12 (22.6) | 2 (10.5) | 11 (15.7) |
MMMT, malignant mixed Müllerian tumor; FIGO, International Federation of Gynecology and Obstetrics.
aNs may not sum to the total because of missing or unknown data; proportions (%) sum to 100% of observations where data was available and excludes missing/unknowns.
bOther epithelial include mixed subtypes where serous or clear cell component does not reach the percentage noted, or where the histology was unknown (2 individuals were diagnosed by curettage).