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. 2020 Feb 27;11:1082. doi: 10.1038/s41467-020-14960-3

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 7 — The chart shows the introduction threshold frequencies for drive homozygotes as a function of the drive fitness cost in homozygotes using a deterministic model of a single panmictic population. These thresholds represent unstable equilibria above which the drive increases in frequency and below which the drive is removed. All drives are idealized, and the underdominance system uses a single locus with heterozygote disadvantage^44,51.