Table 1.

Tumor sites with suspected bacterial communities.

Tumor site	Description	Bacterial community	References
Breast	Tumor tissue has microbial signature similar to surrounding tissue Tumor adjacent tissue significantly different to non-cancer patient breast tissue	Enterobacteriacae spp. (Proteobacteria), Gammaproteobacteria spp. (Proteobacteria), Acinetobacter spp. (Proteobacteria), Bacillus spp. (Firmicutes), Staphylococcus spp. (Firmicutes), and Lactococcus spp. (Firmicutes) Bacteria found in healthy breast tissue: Micrococcus spp. (Actinobacteria) and Prevotella spp. (Bacteroidetes), and to lesser extend Lactococcus spp. and Gammaproteobacteria also found in cancer-related tissue	(1–3)
Pancreatic Ductal Adenocarcinomas (PDAC)	The cancerous pancreas has a more abundant microbiota than healthy control The gut microbiome responsible for ~25% of the tumor microbiome, but was absent from normal adjacent tissue	Enterobacteriaceae, Pseudomonadaceae and to a lesser extent Streptococcaceae, Staphylococcaceae and Micrococcaceae	(5, 11)
Prostatic cancer	Tumor and adjacent tissue significantly different from non-tumor prostate specimens	Actinobacteria, Firmicutes and Proteobacteria, Lactobacillales and Streptococcaceae significantly elevated in healthy samples, Staphylococcacea in tumor and peritumor	(12)
Colorectal cancer	CRC tumor tissue has microbial signature similar to surrounding tissue CRC-associated microbiota profiles, both malignant and non-malignant, differ from healthy controls	Bacteroides, Roseburia, Ruminococcus, Oscillobacter, and oral pathogens such as Fusobacterium elevated in CRC patients	(13)
Others	Ovarian and lung cancer tumor microenvironments have also been characterized		(14, 15)