Figure 2.

Dulaglutide treatment increased muscle fiber size in disuse-induced skeletal muscle atrophy. (A) GA muscle tissue sections were stained with H&E and examined under microscope. (B) The cross-sectional area (CSA) of muscle fiber was measured using ImageJ program and the average CSA is shown. (C) Distribution of myofiber size. Data are shown as means ± S.E.M, n = 5; *p < 0.05, **p < 0.01, ***p < 0.001 versus control + vehicle or immobilization + vehicle group. CV, control + vehicle; CD, control + dulaglutide; IV, immobilization + vehicle; ID, immobilization + dulaglutide.