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. 2020 Feb 21;8:112. doi: 10.3389/fbioe.2020.00112

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Copyright © 2020 Zhao, Yang, Calvelli, Cao, Francis, Chmielowski, Joseph, Pang, Uhrich, Baum and Moghe.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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[FAA:TA] NP uptake pathway studies with different endocytosis inhibitors. BV2 microglia cells were pretreated with different endocytosis pathway inhibitors at corresponding concentration for 1 h, after which the treatment were removed and fluorescently labeled NPs was added in the presence of pathway inhibitors for 3 h. CH: Chlorpromazine hydrochloride; AHH: Amiloride hydrochloride hydrate; GEN: Genistein; MC: Methyl-β-cyclodextrin (Error bar shows standard error of n = 3). ****P < 0.0001 for control vs. CH and control vs. AHH, **P = 0.0049 for control vs. GEN by one-way ANOVA.