Table 1.
Histological measurements in the immediate and conventional models. Statistical analyses were performed with Student’s t-test. The statistical significance level was p 0.05. *Bone graft area directly contacting the bone. †The re-osseointegration height was measured from the bottom of the defect to the first BIC. ‡Vertical bone fill (percentage) was calculated as the ratio of the re-osseointegration height to the defect depth.
| Side | Measurements | Immediate | Conventional | Difference | p-value |
|---|---|---|---|---|---|
| Buccal side | Defect depth | 4.5 (0.6) | 3.6 (0.8) | 0.9 | 0.023 |
| Newly formed bone area (mm2) | 0.9 (0.5) | 4.4 (3.1) | −3.5 | 0.010 | |
| Area of the bone graft (mm2)* | 0.2 (0.2) | 1.6 (1.9) | −1.4 | 0.081 | |
| Total mineralized tissue area (mm2) | 1.1 (0.7) | 6 (4.6) | −4.9 | 0.016 | |
| Re-osseointegration height (mm)† | 1.3 (0.7) | 2 (0.4) | −0.7 | 0.031 | |
| Vertical bone fill (percentage)‡ | 29.0 (16.4) | 60.0 (25.1) | −31.0 | 0.016 | |
| Lingual side | Defect depth (mm) | 4.2 (0.8) | 3.5 (0.3) | 0.8 | 0.031 |
| Newly formed bone area (mm2) | 2.1 (1.1) | 3.6 (1.7) | −1.5 | 0.080 | |
| Area of bone graft (mm2) | 0.2 (0.2) | 0.9 (0.7) | −0.7 | 0.021 | |
| Total mineralized tissue area (mm2) | 2.4 (1.1) | 4.5 (2.2) | −2.1 | 0.042 | |
| Re-osseointegration height (mm)† | 1.6 (0.9) | 2.4 (0.5) | −0.8 | 0.031 | |
| Vertical bone fill (percentage)‡ | 39.6 (26.1) | 70.9 (15.9) | −31.3 | 0.017 |