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. 2020 Jan 7;6(1):e000928. doi: 10.1136/rmdopen-2019-000928

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© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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Change from baseline in fatigue numeric rating scale (NRS) score was evident in associations with week 12 and 24 ACR outcomes (NRI), intent-to-treat population, last observation carried forward. Effect size is defined as the magnitude of change from baseline divided by baseline SD. ^‡p<0.001 versus anchor not met, from analysis of covariance model, including anchor status and baseline fatigue NRS score. ‘Anchor’ refers to ACR50 or 20 responder if ‘anchor met’, and non-responder if ‘anchor not met’. ACR20, American College of Rheumatology 20% response rate; ACR50, American College of Rheumatology 50% response rate; ES, effect size; NRI, non-responder imputation.