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. 2020 Feb 10;6(1):e001102. doi: 10.1136/rmdopen-2019-001102

Table 3.

Results of a subanalysis of 1220 patients with rheumatoid arthritis (RA)

N All-cause mortality at 30 days n (%) HRs 30-day mortality All-cause mortality at 90 days n (%) HRs 90-day mortality
Crude Adjusted* Adjusted† Crude Adjusted* Adjusted†
CRP <8 mg/L 106 5 (4.7) 1 (ref) 1 (ref) 1 (ref) 6 (5.7) 1 (ref) 1 (ref) 1 (ref)
CRP ≥8–19.9 mg/L 207 14 (6.8) 1.45 (0.52 to 4.01) 1.42 (0.51 to 3.95) 1.42 (0.51 to 3.95) 20 (9.7) 1.74 (0.70 to 4.33) 1.68 (0.69 to 4.18) 1.68 (0.67 to 4.18)
CRP ≥20 mg/L 391 70 (17.9) 4.03 (1.63 to 9.99) 3.56 (1.43 to 8.85) 3.64 (1.46 to 9.08) 110 (28.1) 5.58 (2.45 to 12.69) 4.98 (2.19 to 11.36) 4.91 (2.15 to 11.22)
CRP (increase by 10) 704 89 (12.6) 1.04 (1.02 to 1.06) 1.04 (1.02 to 1.06) 1.04 (1.02 to 1.06) 136 (19.3) 1.04 (1.03 to 1.06) 1.04 (1.02 to 1.06) 1.04 (1.02 to 1.06)
Platelets <350×109/L 414 48 (11.6) 1 (ref) 1 (ref) 1 (ref) 68 (16.4) 1 (ref) 1 (ref) 1 (ref)
Platelets 350–400×109/L 97 15 (15.5) 1.36 (0.76 to 2.43) 1.38 (0.77 to 2.49) 1.39 (0.77 to 2.49) 23 (23.7) 1.50 (0.94 to 2.41) 1.55 (0.96 to 2.50) 1.54 (0.95 to 2.48)
Platelets ≥400×109/L 170 27 (15.9) 1.40 (0.87 to 2.24) 1.41 (0.88 to 2.27) 1.42 (0.88 to 2.28) 49 (28.8) 1.84 (1.28 to 2.66) 1.87 (1.29 to 2.71) 1.84 (1.27 to 2.66)
Platelets (increase by 20) 681 90 (13.2) 1.01 (0.98 to 1.04) 1.02 (0.99 to 1.04) 1.02 (0.99 to 1.04) 140 (20.6) 1.03 (1.01 to 1.05) 1.03 (1.01 to 1.05) 1.03 (1.01 to 1.05)

HRs, including 95% CI, were calculated using a Cox proportional hazards model. CRP levels and platelet counts were measured 30–90 days prior to pneumonia admission

All-cause mortality in patients with RA following hospitalisation for pneumonia according to disease activity measured by CRP levels and platelet counts within 30–90 days before pneumonia hospitalisation.

*Adjusted for sex, age, level of comorbidity, alcoholism and antibiotic use before admission.

†Adjusted for sex, age, level of comorbidity, alcoholism, antibiotic use and prednisolone use before admission.

CRP, C reactive protein.