Table 3.
Results of a subanalysis of 1220 patients with rheumatoid arthritis (RA)
| N | All-cause mortality at 30 days n (%) | HRs 30-day mortality | All-cause mortality at 90 days n (%) | HRs 90-day mortality | |||||
| Crude | Adjusted* | Adjusted† | Crude | Adjusted* | Adjusted† | ||||
| CRP <8 mg/L | 106 | 5 (4.7) | 1 (ref) | 1 (ref) | 1 (ref) | 6 (5.7) | 1 (ref) | 1 (ref) | 1 (ref) | 
| CRP ≥8–19.9 mg/L | 207 | 14 (6.8) | 1.45 (0.52 to 4.01) | 1.42 (0.51 to 3.95) | 1.42 (0.51 to 3.95) | 20 (9.7) | 1.74 (0.70 to 4.33) | 1.68 (0.69 to 4.18) | 1.68 (0.67 to 4.18) | 
| CRP ≥20 mg/L | 391 | 70 (17.9) | 4.03 (1.63 to 9.99) | 3.56 (1.43 to 8.85) | 3.64 (1.46 to 9.08) | 110 (28.1) | 5.58 (2.45 to 12.69) | 4.98 (2.19 to 11.36) | 4.91 (2.15 to 11.22) | 
| CRP (increase by 10) | 704 | 89 (12.6) | 1.04 (1.02 to 1.06) | 1.04 (1.02 to 1.06) | 1.04 (1.02 to 1.06) | 136 (19.3) | 1.04 (1.03 to 1.06) | 1.04 (1.02 to 1.06) | 1.04 (1.02 to 1.06) | 
| Platelets <350×109/L | 414 | 48 (11.6) | 1 (ref) | 1 (ref) | 1 (ref) | 68 (16.4) | 1 (ref) | 1 (ref) | 1 (ref) | 
| Platelets 350–400×109/L | 97 | 15 (15.5) | 1.36 (0.76 to 2.43) | 1.38 (0.77 to 2.49) | 1.39 (0.77 to 2.49) | 23 (23.7) | 1.50 (0.94 to 2.41) | 1.55 (0.96 to 2.50) | 1.54 (0.95 to 2.48) | 
| Platelets ≥400×109/L | 170 | 27 (15.9) | 1.40 (0.87 to 2.24) | 1.41 (0.88 to 2.27) | 1.42 (0.88 to 2.28) | 49 (28.8) | 1.84 (1.28 to 2.66) | 1.87 (1.29 to 2.71) | 1.84 (1.27 to 2.66) | 
| Platelets (increase by 20) | 681 | 90 (13.2) | 1.01 (0.98 to 1.04) | 1.02 (0.99 to 1.04) | 1.02 (0.99 to 1.04) | 140 (20.6) | 1.03 (1.01 to 1.05) | 1.03 (1.01 to 1.05) | 1.03 (1.01 to 1.05) | 
HRs, including 95% CI, were calculated using a Cox proportional hazards model. CRP levels and platelet counts were measured 30–90 days prior to pneumonia admission
All-cause mortality in patients with RA following hospitalisation for pneumonia according to disease activity measured by CRP levels and platelet counts within 30–90 days before pneumonia hospitalisation.
*Adjusted for sex, age, level of comorbidity, alcoholism and antibiotic use before admission.
†Adjusted for sex, age, level of comorbidity, alcoholism, antibiotic use and prednisolone use before admission.
CRP, C reactive protein.