Table 1.

Definition of treatment response, remission, relapse, and recovery

Treatment response
	1. Considering positive and negative symptoms simultaneously
	2. ≥30% or ≥50% decrease in the total PANSS score
	3. All seven positive items on the PANSS could be used for decision
	4. Score of 1 or 2 on the CGI-I
	5. After 4 weeks for decision making
Remission
	1. Score of ≤2 on positive and negative PANSS items simultaneously
	2. All seven positive items on the PANSS could be used for decision
	3. In case of using the SANS, score of ≤2 on all items
	4. CGI-S score ≤3
	5. Maintaining 12 months of symptom stabilization period
Relapse (any of one with exacerbation of symptoms ≥6 months after remission)
	1. Psychiatric hospitalization
	2. ≥25% increase in the total PANSS score
	3. Deliberate self-injury, clinically serious suicide or homicide ideation, or suicide attempt
	4. Violent behavior resulting in significant injury to another person or property
	5. Score ≥6 for a PANSS item (P7 hostility or G8 uncooperativeness) within 2 consecutive days
	6. CGI-I score ≥6 (much worse) or 7 (very much worse)
	7. Score ≥4 for CGI-S with an increase ≥2 points
	8. Exacerbation of symptoms ≥6 months after remission
Recovery
	Partial
		1. All criteria fulfilled for ≥1 year
		2. a) Maintaining age-appropriate interpersonal relationships
		b) Employment for entire remission period or homemakers performing housework to some extent
		3. Score of ≤3 on PANSS or SANS items
		4. ≤300 mg of chlorpromazine (or 3 mg of risperidone) equivalent dose
		5. CGI-S score ≤3 (mildly ill)
		6. GAF or SOFAS ≥61
	Full
		1. All criteria fulfilled for ≥1 year
		2. Maintaining age-appropriate socio-occupational functioning
		3. Absent on PANSS or SANS items
		4. No medication
		5. CGI-S score ≤1 (normal, not at all ill)
		6. GAF or SOFAS ≥71

CGI-S: Clinical Global Impression-Severity, CGI-I: Clinical Global Impression of Improvement, PANSS: Positive and Negative Syndrome Scale, SANS: Scale for the Assessment of Negative Symptoms, GAF: Global Assessment of Functioning, SOFAS: Social and Occupational Functioning Assessment Scale