Table 3.
Group comparisons of striatal functional connectivity between OCD patients and HCs
| Seed | Brain region | Cluster size (voxels) | Connectivity strength |
FDR-and Bonferroni-corrected p | MNI coordinates (mm) |
|||
|---|---|---|---|---|---|---|---|---|
| HC | OCD | x | y | z | ||||
| Dorsal caudal putamen (left) | OCD>HC | |||||||
| Right intracalcarine cortex | 341 | -0.10 | 0.04 | 0.001 | 2 | -76 | 4 | |
| HC>OCD | ||||||||
| Left putamen | 192 | 0.26 | 0.11 | 0.043 | -28 | 4 | 4 | |
| Ventral rostral putamen (right) | OCD>HC | |||||||
| Right inferior frontal gyrus | 231 | -0.02 | 0.11 | 0.025 | 56 | 18 | -6 | |
| Left supramarginal gyrus | 220 | -0.05 | 0.08 | 0.025 | -52 | -42 | 32 | |
| Right postcentral gyrus | 187 | -0.02 | 0.12 | 0.049 | 60 | -14 | 22 | |
| Right supramarginal/angular gyrus | 160 | -0.05 | 0.09 | 0.049 | 68 | -40 | 28 | |
FDR: false discovery rate, MNI: Montreal Neurological Institute, OCD: obsessive-compulsive disorder, HCs: healthy controls