Table 2.

Comparisons of %TIR Across All Glycemic Ranges Generated by Different Data Imputation Methodologies, That Is, rtCGM, SMBG Last Observation Carry Forward Method, and SMBG Using Linear Interpolation (n = 226)

Glycemic ranges (%time)	Median %time (IQR)			Kruskal–Wallis (P-value)
	rtCGM	SMBG (carry forward method)	SMBG (linear interpolated)
TIR
3.9–10 mmol/L (70–180 mg/dL)	63.0 (55.9–71.0)	54.6 (45.3–63.0)	61.4 (50.1–69.5)	<0.001a–c
TBR
<3.9 mmol/L (70 mg/dL)	3.5 (1.8–5.1)	3.9 (2.0–6.3)	1.6 (0.8–3.3)	<0.001a–c
<3.0 mmol/L (54 mg/dL)	0.8 (0.3–1.3)	0.7 (0.3–1.5)	0.4 (0.1–0.6)	<0.001b,c
TAR
>10 mmol/L (180 mg/dL)	33.4 (25.1–41.3)	40.1 (31.6–51.3)	35.6 (26.5–48.2)	<0.001a–c
>15 mmol/L (270 mg/dL)	5.0 (2.7–8.2)	8.6 (4.5–13.3)	4.5 (2.0–8.7)	<0.001a,b,d

^aSignificant difference between rtCGM and SMBG carry forward method (P < 0.001).

^bSignificant difference between SMBG using linear interpolation and carry forward method (P < 0.001).

^cSignificant difference between SMBG using linear interpolation and rtCGM (P < 0.001).

^dSignificant difference between SMBG using linear interpolation and rtCGM for TAR >15 mmol/L; >270 mg/dL (P = 0.01).

TAR, time above range; TBR, time below range; TIR, time in range.