. 2020 Feb 14;30(2):204–213. doi: 10.1089/thy.2019.0156

Table 2.

Three Missense Variants in Shelterin Genes in 24 Nonmedullary Thyroid Cancer Families

Family	Genomic position^a	dbSNP	GnomAD	REF	ALT	Gene	Ref. gene	Amino acid change	SIFT	Polyphen
Family 1	chr14:24709044	rs1464083474	0.00003	C	G	TINF2	NM_001099274	p.Val439Leu	Tolerated	Benign
Family B^b	chr14:24711465	rs202093758	0.00177	C	G	TINF2	NM_012461	p.Gly25Ala	Tolerated	Benign
Family H^b	chr16:67693939	rs142662151	0.00035	C	T	ACD	NM_001082486	p.Asp123Asn	Deleterious	Possibly damaging

^{^a}

Genomic position: GRCh37.p13.

^{^b}

The families B and H and the WGS data have been reported (11).

ALT, altered allele; REF, reference allele; WGS, whole genome sequencing.