FIG. 6.

Suppression of keratin expression program occurs during larva to juvenile transitory phase of homozygous thrab 1-bp insertion (m/m) mutant fish. (A) The expression of keratin genes (krt4, krt5, krt15, krt17, and krt18) and skin-regulated genes (col1a1b, cyt1, and cki) from dissected skin tissue on the belly of WT and homozygous thrab 1-bp insertion (m/m) mutant fish at larvae (15 dpf) (number of fish = 64–46) and (B) at juvenile (28 dpf) stage. The expression of the keratin genes was measured by RT-qPCR as described in Materials and Methods section. The data are expressed as mean ± SE (n = 3–6; the p-values are indicated). Two-tail unpaired t-test, p-adjusted <0.05 was used for statistical analysis.