FIG. 1.

Comparison of the glycemic response for each cohort during the hybrid closed-loop phase compared to the standard therapy phase. Sensor glucose versus time of day for the adult (A), adolescent (B), and pediatric (C) participants during 96 h of hybrid closed-loop control (blue dashed line), with data from 1 week of standard therapy shown as comparison (red, solid line). The data are presented as median (line) and interquartile range (shaded area) of sensor glucose per time of day across all participants and days. The target range of 70–180 mg/dL is indicated by black dashed lines.