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. 2020 Feb 21;10:1688. doi: 10.3389/fphar.2019.01688

Table 2.

Consensus statements of EGb from the Asian Clinical Expert Group on Neurocognitive Disorders.

No Consensus statement Concrete content
1 Efficacy of EGb 761® in AD, VaD, and BPSD Best practice for the pharmacological treatment as follows:
AD: AChEI, memantine, EGb
VaD: AChEI, memantine, EGb, antiplatelet therapy
BPSD: ChEI, nonpharmacological treatment, antipsychotics (off-label), memantine, SSRIs, sedatives, and EGb
2 Management of MCI EGb may be considered for use in patients with MCI
3 How to use EGb EGb can be used as a single agent, and allow sufficient time to take effect
4 The dosage EGb at daily dose of 240 mg
5 Lack of efficacy or intolerance of standard drugs may warrant use of EGb EGb was recommended to treat AD, VaD, and mixed dementia, when the patients unable to tolerate the side effects of standard treatments
6 Adjunctive therapies EGb was one of the key management options adjunctive to standard pharmacological therapy for AD, VaD, and BPSD
7 Management of comorbidities EGb played an important role in the management of co-morbidities, such as hypertension, in patients with AD, VaD, and BPSD
8 Does not appear to prevent dementia EGb was not recommended for prevention of dementia
9 Well tolerated EGb had a good tolerability profile in the treatment of MCI, AD, VaD, and BPSD
10 No overall increased bleeding risk EGb appeared to be no overall added risk of bleeding
11 No significant interaction with anticoagulants or antiplatelet agents EGb had been demonstrated no significant interaction with anticoagulants and antiplatelet agents

AD, Alzheimer’s disease; VaD, vascular dementia; BPSD, behavioral and psychological symptoms of dementia; MCI, mild cognitive impairment; AChEI, acetylcholinesterase inhibitors; SSRIs, Selective Serotonin Reuptake Inhibitors.

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