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. 2020 Feb 21;11:99. doi: 10.3389/fphar.2020.00099

Table 2.

Effect of BZP on density and distribution of necrosis in MCAO rats.

Group Dose
(mg/kg)
n Cortex (%) Hippocampal (%) Striatum (%)
Sham 10 6.33 ± 1.93 5.95 ± 1.64 5.12 ± 1.55
Model 10 60.98 ± 9.29** 57.22 ± 9.10** 41.11 ± 6.43**
BZP 0.6 10 58.23 ± 4.78 55.13 ± 8.45 40.17 ± 6.63
1.2 10 50.76 ± 3.57# 47.49 ± 9.08# 34.57 ± 7.09#
2.5 10 39.31 ± 4.96## 36.29 ± 7.85## 27.13 ± 7.21##
5 10 29.14 ± 2.96## 24.04 ± 6.42## 19.02 ± 5.73##
10 10 19.31 ± 4.51##▲▲ 15.03 ±2.40##▲▲ 12.32 ±1.77##▲▲
20 10 20.97 ± 2.25## 14.20 ± 5.06## 12.66 ± 3.87##
C8E4 10 10 47.98 ± 9.44## 44.16 ± 10.7## 29.02 ± 4.36##

Data were represented by mean ± standard deviation. **P < 0.01 vs Sham group; #P < 0.05, ##P < 0.01 vs Model group; ▲▲P < 0.01 vs C8E4 group.