Table 3.
Live vectored and DNA sub-unit vaccine candidates.
| ASFV proteins/genes | Expression system | Protection | References |
|---|---|---|---|
| Vectored p54, p30, sHA | BacMam-sHAPQ | Partial protection | (49) |
| p72, CD2v, and EP153R | Modified vaccinia virus ankara | No challenge study | (61) |
| 7 and 12 antigen cocktails | Adenovirus vectored | No challenge study | (62, 63) |
| 7 antigen cocktail | Adenovirus vectored | Partial protection | (64) |
| 7 antigen cocktail | Adenovirus vectored | No protection | (64) |
| 12 antigen cocktail | Adenovirus vectored | No protection | (64) |
| p30, p54, and pHA-72 | Alphavirus vectored prime, | No challenge study | (65) |
| Attenuated OURT88/3 boost | |||
| 18 antigen cocktail | Adenovirus and MVA vectored | No protection | (66) |
| DNA sub-units DNA expression library |
DNA constructs | Partial protection | (67) |
| p54/E183L, p30/CP204L | DNA constructs | No protection | (68, 69) |
| Ubiquitin-CD2v/pEP402R- p54/E183L-p30/CP204L | DNA constructs | Partial protection | (69) |
| DNA and vectored/protein 47 antigen pool |
DNA constructs and vaccinia virus | Partial protection | (70) |
| p15, p35, p54, and ±p17 and p32, p72, CD2v, and ±p17 | DNA and protein vaccine | No protection | (71) |